Tumour necrosis factor-dependent inflammatory cartilage destruction
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چکیده
منابع مشابه
Signal transduction by tumour necrosis factor and tumour necrosis factor related ligands and their receptors.
Many biological functions are regulated through interactions of extracellular molecules with their cognate cell surface receptors. The transduction of these signals by their receptors at the plasma membrane to the intracellular machinery results in such cellular activities as gene activation, protein phosphorylation, cell proliferation, and cell destruction. Though the kinetics of these activit...
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Acute Gram-negative bacterial infections evoke characteristic pathophysiological responses, including changes in white blood cell counts, fever, haemodynamic disorders, and various coagulatory disturbances, which may result in respiratory distress syndrome, multiorgan failure and irreversible shock. It is generally accepted that endotoxins, the lipopolysaccharides (LPS) of Gramnegative bacteria...
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Tumour necrosis factor-alpha (TNF-alpha) was measured by enzyme-linked immunosorbent assay and eosinophil cationic protein (ECP) by radio-immunoassay to evaluate TNF-alpha in nasal allergy. There was no significant difference either between the mean concentrations of TNF-alpha in nasal secretions from the patients with perennial nasal allergy and those of normal subjects, or between the TNF-alp...
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ژورنال
عنوان ژورنال: Arthritis Research & Therapy
سال: 2007
ISSN: 1478-6354
DOI: 10.1186/ar2230